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Siponimod
Siponimod

Artikelnummer: TGM-T6403-100mg

Description: BAF312 (Siponimod (BAF-312)), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibits >1000-fold over S1P2, S1P3 and S1P4 receptors. Target: LPL Receptor, S1P...
Schlagworte: BAF-312
Anwendung: Targets sphingosine 1-phosphate receptor 1 (S1PR1, EDG1, CD363)
CAS 1230487-00-9
MW: 516.59 D
ab 34,00 €
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Siponimod
Siponimod

Artikelnummer: Cay22057-1

Siponimod is an agonist of sphingosine-1-phosphate receptor 1 (S1P1) and S1P5. It is selective for S1P1 and S1P5 over S1P2, S1P3, and S1P4 (EC50s = 0.39, 0.98, >10,000, >1,000, and 750 nM, respectively, in GTP-gammaS binding assays). Siponimod (10 nM) reduces demyelination induced by lysophosphatidylcholine or...
Schlagworte: BAF312,...
Anwendung: S1P receptor agonist
CAS 1230487-00-9
MW: 516.6 D
ab 44,00 €
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Siponimod-D11
Siponimod-D11

Artikelnummer: ESS0520.10mg

Schlagworte: (E)-1-(4-(1-(((4-(Cyclohexyl-d11)-3-(trifluoromethyl)benzyl)oxy)imino)ethyl)-2-ethylbenzyl)azetidine-3-carboxylic Acid
Anwendung: Quantitative determination in biological samples, pharmacokinetic studies
CAS 1230487-00-9
MW: 527.7 D
ab 2.917,00 €
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