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TAK-632
TAK-632

Artikelnummer: TGM-T1886-100mg

Description: TAK-632, a potent pan-Raf inhibitor (GenScript, 2020), is characterized by its molecular weight [M] for [C 22 H 19 FN 2 O 2] of 362.4 by LC-MS, with a purity of 99% (HPLC). The compound exhibits white to off-white solid form and has a melting point [M] ranging from 178°C to 182°C (GenScript, 2020). Its...
Anwendung: RAF inhibitor
CAS 1228591-30-7
MW: 554.52 D
ab 37,00 €
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TAK-632
TAK-632

Artikelnummer: Cay16285-1

TAK-632 is a slow off-rate inhibitor of Raf kinases (IC50s = 8.3, 2.4, and 1.4 nM for wild type B-Raf, mutant B-RafV600E, and c-Raf, respectively). It demonstrates 14-1,200-fold selectivity for Raf over a panel of 26 different kinases. TAK-632 shows significant antiproliferative activity against mutated B-Raf or...
Schlagworte: N-[5-[[7-cyano-2-[(cyclopropylcarbonyl)amino]-6-benzothiazolyl]oxy]-2-fluorophenyl]-3-(trifluoromethyl)-benzeneacetamide
Anwendung: RAF inhibitor
CAS 1228591-30-7
MW: 554.5 D
ab 44,00 €
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TAK-632
TAK-632

Artikelnummer: SYN-1203-M001

Soluble in DMSO or ethanol. Slightly soluble (<1mg/ml) in water.TAK-632 is a potent pan-RAF inhibitor with favorable in vitro activity (BRAF(V600E) IC(50) of 2.4nM. Target: Raf , Kinase Group: TKL , Substrate: Serine-Threonine
Schlagworte: TAK632
Anwendung: Raf inhibitor
CAS 1228591-30-7
MW: 554,5 D
ab 108,00 €
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TAK-632
TAK-632

Artikelnummer: LKT-T0140.1

RAF inhibitor.
Schlagworte: TAK632
Anwendung: RAF inhibitor
CAS 1228591-30-7
MW: 554.52 D
ab 146,00 €
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