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FLLL32
Artikelnummer: TGM-T6838-100mg
Description: FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 µM). Target: Apoptosis, STAT, JAK. Smiles: COc1ccc(\C=C\C(=O)C2(CCCCC2)C(=O)\C=C\c2ccc(OC)c(OC)c2)cc1OC. References: Lin L, et al. Cancer Res. 2010, 70(6), 2445-2454.
| Anwendung: | STAT3 inhibitor |
| CAS | 1226895-15-3 |
| MW: | 464.55 D |
ab 38,00 €
FLLL32
Artikelnummer: Cay10638-1
FLLL32 is a cell-permeable analog of curcumin (Cay-81025) that inhibits JAK2-mediated phosphorylation of STAT3 on Tyr705 in cancer cells (IC50 = ~5 µM). It blocks signaling from IFN-alpha or IL-6 through JAK2/STAT3 and induces apoptosis in several types of cancer cells. FLLL32 does not interfere with...
| Schlagworte: | JAK2 Inhibitor X, (2E,2'E)-1,1'-cyclohexylidenebis[3-(3,4-dimethoxyphenyl)]-2-propen-1-one |
| Anwendung: | STAT3 inhibitor |
| CAS | 1226895-15-3 |
| MW: | 464.6 D |
ab 53,00 €
