Zu "1223001-51-1" wurden 3 Artikel gefunden!
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Torin 2
Artikelnummer: TGM-T6100-100mg
Description: Torin 2(IC50=0.25 nM), a specific and effective mTOR inhibitor, is the 800-fold greater specific activity for mTOR than PI3K and improves pharmacokinetic properties. The EC50 of Torin 2 for ATM/ATR/DNA-PK inhibition is 28 nM/35 nM/118 nM, respectively. Target: Autophagy, ATM/ATR, mTOR, Apoptosis,...
| Anwendung: | mTOR inhibitor |
| CAS | 1223001-51-1 |
| MW: | 432.4 D |
ab 37,00 €
Torin 2
Artikelnummer: Cay14185-5
Torin 2 is a potent and selective inhibitor of cellular mTOR activity (EC50 = 0.3 nM). It shows more than 800-fold selectivity for mTOR over PI3K (EC50 = 200 nM) and greater than 100-fold binding selectivity relative to 440 other protein kinases. Torin 2 has significantly improved bioavailability (54%), metabolic...
| Schlagworte: | 9-(6-amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-benzo[h]-1,6-naphthyridin-2(1H)-one |
| Anwendung: | mTOR inhibitor |
| CAS | 1223001-51-1 |
| MW: | 432.4 D |
ab 117,00 €
Torin 2
Artikelnummer: LKT-T5871.10
Tricyclic benzonaphthyridinone, mTORC1/2 inhibitor.
| Anwendung: | Tricyclic benzonaphthyridinone, mTORC1/2 inhibitor |
| CAS | 1223001-51-1 |
| MW: | 432.41 D |
ab 219,00 €
