Zu "1222998-36-8" wurden 3 Artikel gefunden!
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Torin 1
Artikelnummer: Cay10997-10
Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-fold selectivity for mTOR over PI3Kalpha and other PI3K-like kinases, including ATM, DNA-PK, and hVps34, as well as 450 other protein kinases. Torin 1, is efficacious at a dose of 20 mg/kg...
| Schlagworte: | 1-[4-[4-(1-oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-benzo[h]-1,6-naphthyridin-2(1H)-one |
| Anwendung: | mTor inhibitor |
| CAS | 1222998-36-8 |
| MW: | 607.6 D |
ab 196,00 €
Torin 1
Artikelnummer: TGM-T6045-100mg
Description: Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM), has 1000-fold selectivity for mTOR than PI3K. Target: mTOR, PI3K, Autophagy, DNA-PK. Smiles: CCC(=O)N1CCN(CC1)c1ccc(cc1C(F)(F)F)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1cnc2ccccc2c1. References: Thoreen CC, et al. An ATP-competitive...
| Anwendung: | mTor inhibitor |
| CAS | 1222998-36-8 |
| MW: | 607.62 D |
ab 31,00 €
Torin 1
Artikelnummer: LKT-T5870.5
Tricyclic benzonaphthyridinone, mTORC1/2 inhibitor.
| Anwendung: | Tricyclic benzonaphthyridinone, mTORC1/2 inhibitor |
| CAS | 1222998-36-8 |
| MW: | 607.64 D |
ab 132,00 €
