Zu "1219810-16-8" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
(1S,3R)-RSL3
Artikelnummer: Cay19288-5
(1S,3R)-RSL3 is a ferroptosis inducer and is canonically known as an inhibitor of glutathione peroxidase 4 (GPX4). It inhibits GPX4 in a context-dependent manner: (1S,3R)-RSL3 inhibits GPX4 in the presence of cell cytosol or recombinant human 14-3-3epsilon, an adaptor protein, but does not inhibit recombinant human...
| Schlagworte: | (1S,3R)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylic acid,... |
| Anwendung: | GPX4 inhibitor |
| CAS | 1219810-16-8 |
| MW: | 440.9 D |
ab 43,00 €
RSL3
Artikelnummer: TGM-T3646-100mg
Description: RSL3 (RSL3 1S) is an inhibitor of GPX4, and inhibits system xc- that blocks GSH synthesis (IC50=100 nM). RSL3 is a VDAC-independent activator of ferroptosis that is selective for tumor cells carrying oncogenic RAS. Target: GPX, Glutathione Peroxidase, Ferroptosis. Smiles:...
| Schlagworte: | 1S,3R-RSL3, RSL3 1S |
| Anwendung: | GPX4 inhibitor |
| CAS | 1219810-16-8 |
| MW: | 440.88 D |
ab 33,00 €
