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4-iodo-SAHA
Artikelnummer: TGM-T21749-100mg
Description: 4-Iodo-SAHA (1k), an orally active inhibitor of both class I and class II histone deacetylase (HDAC), exhibits EC50 values of 1.1, 0.95, 0.12, 0.24, 0.85, and 1.3 µM for Skbr3, HT29, U937, JA16, and HL60 cell lines, respectively. This compound holds potential for cancer research purposes [1]. Target:...
| CAS | 1219807-87-0 |
| MW: | 390.22 D |
ab 218,00 €
4-iodo-SAHA
Artikelnummer: Cay10495-100
4-iodo-SAHA is a hydrophobic derivative of the class I and class II histone deacetylase (HDAC) inhibitor SAHA. At 1 µM it demonstrates >60% inhibition of HDAC1 and HDAC6 activity in a deacetylase activity assay, similar to that of SAHA. 4-iodo-SAHA inhibits proliferation of SK-BR-3 breast-derived and HT29...
| Schlagworte: | N1-hydroxy-N8-(4-iodophenyl) octanediamide |
| Anwendung: | HDAC inhibitor |
| CAS | 1219807-87-0 |
| MW: | 390.2 D |
ab 119,00 €
