Zu "120964-45-6" wurden 2 Artikel gefunden!
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3-deazaneplanocin A HCl
Artikelnummer: TGM-T6360-100mg
Description: 3-deazaneplanocin A HCl is both an S-adenosyl-l-homocysteine hydrolase inhibitor and an enhancer of zeste homolog 2(EZH2) inhibitor. Target: Others, Histone Methyltransferase. Smiles: Cl.Nc1nccc2n(cnc12)C1C=C(CO)C(O)C1O. References: Glazer RI, et al. Biochem Pharmacol, 1986, 35(24), 4523-4527.
| Anwendung: | Apoptosis inducer, trimethylation inhibitor |
| CAS | 120964-45-6 |
| MW: | 298.73 D |
ab 89,00 €
3-Deazaneplanocin A (hydrochloride)
Artikelnummer: Cay11102-500
The lysine methyltransferase EZH2 (KMT6), part of the polycomb repressive complex 2, catalyzes trimethylation of lysine 27 on histone H3 and is involved in proliferation and aggressive cell growth associated with neoplastic cells. 3-Deazaneplanocin A is a cyclopentenyl analog of 3-deazaadenosine, originally...
| Schlagworte: | 2,3-DMMC, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol, monohydrochloride |
| CAS | 120964-45-6 |
| MW: | 298.7 D |
ab 126,00 €
