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CAY10614
Artikelnummer: TGM-T38366-10mg
Description: CAY10614 is a TLR4 antagonist. CAY10614 inhibits lipid A-induced activation of TLR4 (IC50=1.675 µM). CAY10614 also improves survival in LPS-induced shock model mice. Target: Others. Smiles: [I-].CCCCCCCCCC CCCCOc1ccc(C[N+](C)(C)C2CCCC2)cc1OCCCCCCCCCCCCCC
| Schlagworte: | CAY10614 |
| Anwendung: | TLR4 antagonist |
| CAS | 1202208-36-3 |
| MW: | 755.995 D |
ab 135,00 €
CAY10614
Artikelnummer: Cay13615-1
Lipid A is a lipid-rich component of endotoxin, also known as lipopolysaccharide (LPS), which in turn is part of the outer membrane of Gram-negative bacteria. Lipid A activates toll-like receptor 4 (TLR4), initiating an immune response. CAY10614 is an antagonist of lipid A activation of TLR4, exhibiting an IC50...
| Schlagworte: | N-cyclopentyl-N,N-dimethyl-3,4-bis(tetradecyloxy)-benzenemethanaminium, iodide |
| Anwendung: | TLR4 antagonist |
| CAS | 1202208-36-3 |
| MW: | 756 D |
ab 74,00 €
IAXO-103 (CD14/TLR4 Antagonist) (synthetic)
Artikelnummer: IAX-600-003-M001
Described to interfere with human, rat and mouse TLR4/CD14 signaling, other species not tested. Optimal working concentration depends upon the type, purity and concentration and of TLR4 ligand, carrier protein such as LPS-binding protein (LBP), soluble and membrane-bound CD14, the presence of TLR4 co-receptors (e.g....
| Schlagworte: | N-(3,4-bis-Tetradecyloxy-benzyl)-N-cyclopentyl-N,N-dimethylammonium iodide |
| Anwendung: | CD14/TLR4 Antagonist |
| CAS | 1202208-36-3 |
| MW: | 755.98 D |
347,00 €
