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Tofogliflozin (hydrate)
Artikelnummer: TGM-T5016-100mg
Description: Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2, with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2, respectively. Target: ROS, Reactive Oxygen Species, SGLT. Smiles:...
| Schlagworte: | Tofogliflozin hydrate, CSG-452 hydrate |
| Anwendung: | Targets solute carrier family 5 (sodium/glucose cotransporter), member 2 (SLC5A2, SGLT2) |
| CAS | 1201913-82-7 |
| MW: | 404.45 D |
ab 40,00 €
Tofogliflozin (hydrate)
Artikelnummer: Cay23509-10
Tofogliflozin is a potent inhibitor of sodium glucose cotransporter 2 (SGLT2) with Ki values of 2.9, 14.9, and 6.4 nM for human, rat, and mouse SGLT2, respectively. It is selective for SGLT2 (IC50 = 2.9 nM) over other SGLTs (IC50s = >1,500 nM for SGLT1 and 3-6). Tofogliflozin (3-10 mg/kg) reduces plasma glucose...
| Schlagworte: | (1S,3'R,4'S,5'S,6'R)-6-[(4-ethylphenyl)methyl]-3',4',5',6'-tetrahydro-6'-(hydroxymethyl)-spiro[isobenzofuran-1(3H),2'-[2H]... |
| Anwendung: | SGLT-2 inhibitor |
| CAS | 1201913-82-7 |
| MW: | 404.5 D |
ab 44,00 €
