Zu "1201438-56-3" wurden 4 Artikel gefunden!
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Duvelisib
Artikelnummer: TGM-T1988-100mg
Description: Duvelisib (INK1197) is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. Target: PI3K. Smiles:...
| Schlagworte: | IPI-145, INK1197 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 1201438-56-3 |
| MW: | 416.86 D |
ab 42,00 €
IPI-145
Artikelnummer: Cay16800-1
IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3Kgamma and PI3Kdelta (IC50s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3Kgamma and PI3Kdelta are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and...
| Schlagworte: | Duvelisib, INK1197, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone |
| Anwendung: | PI3K gamma / delta inhibitor |
| CAS | 1201438-56-3 |
| MW: | 416.9 D |
ab 94,00 €
IPI-145
Artikelnummer: SYN-1175-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. IPI-145 is a potent, oral inhibitor of Class I phosphoinositide-3-kinase (PI3K)-delta and PI3K-gamma (IC(50) of 243 pM and 50nM), and is clinically active in patients with advanced hematological malignancies. Target: PI3K , Kinase Group: Atypical (PIKK) ,...
| Schlagworte: | IPI 145 |
| Anwendung: | PI3K gamma / delta inhibitor |
| CAS | 1201438-56-3 |
| MW: | 416,9 D |
ab 162,00 €
IPI-145
Artikelnummer: LKT-I6132.1
IPI-145 is an inhibitor of p110 PI3K that exhibits anticancer chemotherapeutic, immunosuppressive, and anti-inflammatory activities. In clinical trials, IPI-145 displays potential benefit in the treatment of chronic lymphocytic leukemia (CLL). IPI-145 inhibits proliferation of B and T cells, inhibits neutrophil...
| Schlagworte: | INK1197 |
| Anwendung: | PI3K gamma / delta inhibitor |
| CAS | 1201438-56-3 |
| MW: | 416.86 D |
ab 215,00 €
