Zu "1199796-29-6" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
INT-777
Artikelnummer: TGM-T11662L-100mg
Description: INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 µM. INT-777 (S-EMCA) inhibits NLRP5-ASC inflammasome-mediated neuroinflammation via the TGR3/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats. Target: GPCR19. Smiles:...
| Schlagworte: | S-EMCA |
| CAS | 1199796-29-6 |
| MW: | 450.65 D |
ab 136,00 €
INT-777
Artikelnummer: Cay17678-500
TGR5 is a transmembrane G protein-coupled receptor that is activated by bile acid. INT-777 is a semisynthetic bile acid that acts as an agonist of TGR5 (EC50 = 0.82 µM). It is active in vivo, stimulating the secretion of glucagon-like peptide 1 (GLP-1) in mice when given orally (30 mg/kg) after a glucose challenge,...
| Schlagworte: | HY-15677, 6-EMCA, S-EMCA, (3alpha,5beta,6alpha,7alpha,12alpha,23S)-6-ethyl-3,7,12-trihydroxy-cholane-23-carboxylic acid |
| Anwendung: | TGR5 agonist |
| CAS | 1199796-29-6 |
| MW: | 450.7 D |
ab 163,00 €
