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Gedatolisib
Artikelnummer: TGM-T1970-100mg
Description: Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kalpha/gamma (IC50: 0.4/5.4 nM)and mTOR (IC50: 1.6 nM) in the PI3K/mTOR signaling pathway. Target: PI3K, mTOR. Smiles: N(C(NC1=CC=C(C(=O)N2CCC(N(C)C)CC2)C=C1)=O)C3=CC=C(C=4N=C(N=C(N4)N5CCOCC5)N6CCOCC6)C=C3. References:...
| Schlagworte: | PF-05212384, PKI-587 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 1197160-78-3 |
| MW: | 615.73 D |
ab 47,00 €
PF-05212384
Artikelnummer: Cay14567-1
Phosphatidylinositol-3-kinases (PI3Ks) act in concert with mTOR complexes to regulate signaling pathways that have critical roles in cancer and other diseases. PF-05212384 is a potent, dual PI3K/mTOR inhibitor (IC50 values are 0.4 and 5.4 nM for PI3Kalpha and PI3Kgamma, respectively, and 1.6 nM for mTOR). It is...
| Schlagworte: | PK-1587, PKI-587,... |
| Anwendung: | PI3K/mTOR inhibitor |
| CAS | 1197160-78-3 |
| MW: | 615.7 D |
ab 52,00 €
