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EMD638683
Artikelnummer: TGM-T6635-100mg
Description: EMD638683,a novel SGK inhibitor with antihypertensive potency(with an IC50 of 3 µM). Target: SGK. Smiles: CCc1c(C)c(O)ccc1C(=O)NNC(=O)C(O)c1cc(F)cc(F)c1. References: Towhid S T , Liu G L , Ackermann T F , et al. Inhibition of Colonic Tumor Growth by the Selective SGK Inhibitor EMD638683[J]. Cellular...
| Anwendung: | Serum- and glucocorticoid-regulated kinase 1 (SGK1) inhibitor |
| CAS | 1181770-72-8 |
| MW: | 364.34 D |
ab 88,00 €
EMD 638683
Artikelnummer: Cay31117-1
EMD 638683 is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) that inhibits SGK1 by 85% when used at a concentration of 1 µM. It is greater than 27-fold selective for SGK1 over a panel of 11 kinases but does inhibit SGK2, SGK3, PRK2, and MSK1 by greater than 50% at 1 µM. EMD 638683 inhibits...
| Schlagworte: | 3,5-difluoro-alpha-hydroxy-benzeneacetic acid, 2-(2-ethyl-4-hydroxy-3-methylbenzoyl)hydrazide |
| Anwendung: | Serum- and glucocorticoid-regulated kinase 1 (SGK1) inhibitor |
| CAS | 1181770-72-8 |
| MW: | 364.3 D |
ab 77,00 €
