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NSC 23766 trihydrochloride
Artikelnummer: TGM-T6342-100mg
Description: NSC 23766 trihydrochloride (Rac1 Inhibitor) is an inhibitor of Rac GTPase targeting Rac activation by GEFs (IC50: ~50 µM), no inhibitory for the closely related targets, RhoA or Cdc42. Target: Rho, Apoptosis, Ras. Smiles: Cl.Cl.Cl.CCN(CC)CCCC(C)Nc1nc(C)cc(Nc2ccc3nc(C)cc(N)c3c2)n1. References: Gao Y,...
| Schlagworte: | Rac1 Inhibitor, NSC 23766 |
| Anwendung: | Rac1 inhibitor |
| CAS | 1177865-17-6 |
| MW: | 530.96 D |
ab 52,00 €
NSC 23766 (hydrochloride)
Artikelnummer: Cay13196-1
Rac1 is a GTPase that is involved in the regulation of the cell cycle, cell-cell adhesion, motility, and differentiation. Rac1 is activated by its interaction with specific guanine nucleotide exchange factors (GEFs). NSC 23766 is a cell-permeable, reversible inhibitor of Rac1 activation by the Rac-specific GEFs...
| Schlagworte: | N6-[2-[[4-(diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine, trihydrochloride |
| Anwendung: | Rac1 inhibitor |
| CAS | 1177865-17-6 |
| MW: | 531 D |
ab 45,00 €
