Zu "1174130-61-0" wurden 2 Artikel gefunden!
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Aticaprant
Artikelnummer: Cay35464-5
Aticaprant is a kappa-opioid receptor (KOR) antagonist (Ki = 0.807 nM). It is selective for KOR over the µ- and delta-opioid receptors (Kis = 24 and 155 nM, respectively). Aticaprant reverses U-69593-induced decreases in nocifensive behavior in the formalin test in rats (ED50 = 0.4 mg/kg). It also reverses...
| Schlagworte: | CERC-501, JNJ-67953964, LY2456302, 4-[4-[[(2S)-2-(3,5-dimethylphenyl)-1-pyrrolidinyl]methyl]phenoxy]-3-fluoro-benzamide |
| Anwendung: | Kappa-opioid receptor antagonist |
| CAS | 1174130-61-0 |
| MW: | 418.5 D |
ab 145,00 €
Aticaprant
Artikelnummer: TGM-TQ0082-100mg
Description: Aticaprant (LY-2456302) (CERC-501) is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM). Target: Opioid Receptor. Smiles: Cc1cc(C)cc(c1)[C@@H]1CCCN1Cc1ccc(Oc2ccc(cc2F)C(N)=O)cc1. References: Rorick-Kehn LM, et al. LY2456302 is a novel, potent, orally-bioavailable...
| Schlagworte: | LY-2456302, CERC-501 |
| Anwendung: | Targets kappa-type opioid receptor (OPRK1) |
| CAS | 1174130-61-0 |
| MW: | 418.5 D |
ab 34,00 €
