Zu "1173022-16-6" wurden 2 Artikel gefunden!
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RS102895 hydrochloride
Artikelnummer: TGM-T12773-100mg
Description: RS102895 hydrochloride is a potent antagonist of CCR2(IC50 of 360 nM). Target: CCR, 5-HT Receptor, Others. Smiles: Cl.FC(F)(F)c1ccc(CCN2CCC3(CC2)OC(=O)Nc2ccccc32)cc1. References: Mirzadegan T, et al. Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding...
| Anwendung: | CCR2 antagonist |
| CAS | 1173022-16-6 |
| MW: | 426.86 D |
ab 40,00 €
RS 102895 (hydrochloride)
Artikelnummer: Cay18207-10
The chemokine CCL2, also known as monocyte chemotactic protein-1 (MCP-1), stimulates leukocyte chemotaxis to sites of inflammation via signaling through the MCP-1 receptor, CCR2. RS 102895 is a spiropiperidine compound that acts as a CCR2 antagonist (IC50 = 0.36 µM). It inhibits the related CCR1 receptor with an...
| Schlagworte: | 1'-[2-[4-(trifluoromethyl)phenyl]ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one, monohydrochloride |
| Anwendung: | CCR2 antagonist |
| CAS | 1173022-16-6 |
| MW: | 426.9 D |
ab 46,00 €
