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HO-3867
Artikelnummer: TGM-T6537-100mg
Description: HO-3867, an analog of curcumin, is a sspecific STAT3 inhibitor. Target: Apoptosis, STAT. Smiles: CC1(C)C=C(CN2C\C(=C/c3ccc(F)cc3)C(=O)\C(C2)=C\c2ccc(F)cc2)C(C)(C)N1O. References: Selvendiran K, et al. Mol Cancer Ther. 2010, 9(5), 1169-1179.
| Schlagworte: | HO3867 |
| Anwendung: | STAT3 inhibitor |
| CAS | 1172133-28-6 |
| MW: | 464.55 D |
ab 48,00 €
HO-3867
Artikelnummer: Cay21581-5
HO-3867 is an analog of curcumin (Cay-81025) that selectively suppresses STAT3 phosphorylation, transcription, and DNA binding without affecting the expression of other active STATs. It has been shown to induce apoptosis in BRCA-mutated ovarian cancer cells with minimal toxicity to normal cells. HO-3867 is reported...
| Schlagworte: | (3E,5E)-1-[(2,5-dihydro-1-hydroxy-2,2,5,5-tetramethyl-1H-pyrrol-3-yl)methyl]-3,5-bis[(4-fluorophenyl)methylene]-4-piperidi... |
| Anwendung: | STAT3 inhibitor |
| CAS | 1172133-28-6 |
| MW: | 464.6 D |
ab 78,00 €
