Zu "114899-77-3" wurden 2 Artikel gefunden!
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Trabectedin
Artikelnummer: TGM-T17155-1mg
Description: Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0.1 nM, 1.5 nM and 3.7 nM, respectively. Target: Reactive Oxygen Species, Apoptosis....
| Schlagworte: | Ecteinascidin 743, ET-743 |
| Anwendung: | Antineoplastic, Alkylating agent |
| CAS | 114899-77-3 |
| MW: | 761.84 D |
ab 261,00 €
Trabectedin
Artikelnummer: Cay34662-1
Trabectedin is an alkaloid that has been found in E. turbinata and has anticancer activity. It is a guanine-specific DNA alkylating agent and an antagonist of the pregnane X receptor (PXR, IC50 = ~3 nM in a reporter assay). Trabectedin reduces viability of DU145 and PC3 human prostate cancer stem cells in a...
| Schlagworte: | Ecteinascidin 743, ET-743, NSC 648766,... |
| Anwendung: | Alkaloid, anticancer agent, PXT antagonist, guanine-specific DNA alkylating agent |
| CAS | 114899-77-3 |
| MW: | 761.8 D |
ab 264,00 €
