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Tripolin A
Artikelnummer: TGM-T8537-25mg
Description: Tripolin A is a specific non-ATP competitive inhibitor of Aurora A kinase(Aurora A and Aurora B with IC50 values of 1.5 µM and 7 µM, respectively). Target: Aurora Kinase. Smiles: C(=C/1\C=2C(NC1=O)=CC=CC2)\C3=C(O)C=CC(O)=C3. References: Iliana A Kesisova, et al. Tripolin A, a Novel Small-Molecule...
| Anwendung: | Aurora A kinase inhibitor |
| CAS | 1148118-92-6 |
| MW: | 253.25 D |
800,00 €
Tripolin A
Artikelnummer: AG-CR1-3520-M001
Soluble in DMSO (at least 10 mg/ml). Specific non-ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, spindle formation and length and MT dynamics in interphase.
| Schlagworte: | (3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one |
| Anwendung: | Aurora A kinase inhibitor |
| CAS | 1148118-92-6 |
| MW: | 253,3 D |
ab 88,00 €
