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Avagacestat
Artikelnummer: TGM-T6249-100mg
Description: Avagacestat (BMS-708163) (BMS-708163) is a potent, selective, orally bioavailable gamma-secretase inhibitor of Abeta40 and Abeta42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2. Target: Gamma-secretase. Smiles:...
| Schlagworte: | BMS-708163 |
| Anwendung: | Dementia therapeutic agent, gamma-Secretase inhibitor |
| CAS | 1146699-66-2 |
| MW: | 520.89 D |
ab 57,00 €
Avagacestat
Artikelnummer: Cay16711-1
gamma-Secretase is a protease complex that cleaves single-pass transmembrane proteins, such as Notch receptors and beta-amyloid precursor protein (APP), within the transmembrane domain. Avagacestat is a potent, orally bioavailable inhibitor of gamma-secretase that more potently inhibits the cleavage of APP to...
| Schlagworte: | BMS 708163,... |
| Anwendung: | gamma-secretase inhibitor |
| CAS | 1146699-66-2 |
| MW: | 520.9 D |
ab 61,00 €
BMS-708163
Artikelnummer: LKT-B5075.1
gamma-Secretase inhibitor.
| Schlagworte: | Avagacestat, BMS708163 |
| Anwendung: | gamma-secretase inhibitor |
| CAS | 1146699-66-2 |
| MW: | 520.88 D |
ab 94,00 €
