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E-4031
E-4031

Artikelnummer: TGM-T7198-100mg

Description: E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs cardiac action potential duration by blocking ERG K+ channels (IC50 = 29 nM). Target: EGFR, Potassium Channel. Smiles: Cl.Cl.Cc1cccc(CCN2CCC(CC2)C(=O)c2ccc(NS(C)(=O)=O)cc2)n1. References: David Z , Julia B , Gerlind F , et...
Anwendung: ERG K+ channel blocking
CAS 113559-13-0
MW: 474.44 D
ab 38,00 €
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E-4031 (hydrochloride)
E-4031 (hydrochloride)

Artikelnummer: Cay15203-5

Voltage-gated potassium ERG channels (Kv11.1), encoded by the ether-a-go-go related gene, mediate the inwardly rectifying potassium (K+) current that repolarizes myocardial cells, gut smooth muscle cells, and interstitial cells of Cajal. E-4031 is a methanesulfonanilide class III antiarrhythmic agent that prolongs...
Schlagworte: N-[4-[[1-[2-(6-methyl-2-pyridinyl)ethyl]-4-piperidinyl]carbonyl]phenyl]-methanesulfonamide, dihydrochloride
Anwendung: ERG K+ channel blocking
CAS 113559-13-0
MW: 474.4 D
ab 109,00 €
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