Zu "1135242-13-5" wurden 2 Artikel gefunden!
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VU0357017 hydrochloride
Artikelnummer: TGM-T3619-100mg
Description: VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM, Pec50: 6.37 ± 0.15). Target: AChR. Smiles: Cl.CCOC(=O)N1CCC(CC1)NCCNC(=O)c1ccccc1C. References: Digby GJ, et al. ACS Chem Neurosci. 2012 Dec...
| Schlagworte: | ML071 hydrochloride, VU 0357017 hydrochloride, CID-25010775 |
| Anwendung: | M1 muscarinic acetylcholine allosteric agonist |
| CAS | 1135242-13-5 |
| MW: | 369.89 D |
ab 35,00 €
VU0357017 (hydrochloride)
Artikelnummer: Cay11939-1
VU0357017 is an allosteric agonist of M1 muscarinic acetylcholine receptors (mAChRs, Ki = 9.91 µM in CHO cells). In vitro, it is selective for M1 over M2-M5 mAChRs (Kis = 21.4-50 µM in CHO cells). VU0357017 induces concentration-dependent increases in calcium mobilization and activates the ERK signaling pathway with...
| Schlagworte: | CID-25010775, 4-[[2-[(2-methylbenzoyl)amino]ethyl]amino]-1-piperidinecarboxylic acid, ethyl ester, monohydrochloride |
| Anwendung: | M1 muscarinic acetylcholine allosteric agonist |
| CAS | 1135242-13-5 |
| MW: | 369.9 D |
ab 34,00 €
