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Salermide
Salermide

Artikelnummer: TGM-T3953-100mg

Description: Salermide, an inhibitor of Sirt1 and Sirt2, induces cancer-specific apoptotic cell death. Target: Sirtuin, Apoptosis. Smiles: CC(C(=O)Nc1cccc(c1)\N=C\c1c(O)ccc2ccccc12)c1ccccc1. References: Lara E, et al. Oncogene. 2009, 28(6):781-91.
Anwendung: SIRT inhibitor
CAS 1105698-15-4
MW: 394.47 D
ab 42,00 €
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Salermide
Salermide

Artikelnummer: Cay13178-10

The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to, e.g., longevity, cancer, gene regulation, energy homeostasis, and apoptosis. Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells,...
Schlagworte: N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-a-methyl-benzeneacetamide
Anwendung: SIRT inhibitor
CAS 1105698-15-4
MW: 394.5 D
ab 69,00 €
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Salermide
Salermide

Artikelnummer: LKT-S0344.10

Salermide is an inhibitor of sirtuins that exhibits anti-parasitic and anticancer chemotherapeutic activities. In Schistosoma mansoni, salermide decreases egg-laying activity, disrupts morphology of reproductive organs, and induces apoptosis and cell death. In breast cancer cells, salermide downregulates expression...
Anwendung: SIRT inhibitor
CAS 1105698-15-4
MW: 394.47 D
ab 177,00 €
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