Zu "1101854-58-3" wurden 2 Artikel gefunden!
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JZL 184
Artikelnummer: Cay13158-5
Endocannabinoids such as 2-arachidonoyl glycerol (2-AG) and arachidonoyl ethanolamide (AEA) are biologically active lipids that are involved in a number of synaptic processes including activation of cannabinoid receptors. Monoacylglycerol lipase (MAGL) is a serine hydrolase responsible for the hydrolysis of 2-AG to...
| Schlagworte: | 4-nitrophenyl-4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate |
| Anwendung: | Selective, potent monoglyceride lipase (MGL) inhibitor |
| CAS | 1101854-58-3 |
| MW: | 520.5 D |
ab 61,00 €
JZL 184
Artikelnummer: TGM-T6554-100mg
Description: JZL 184 is a potent and selective inhibitor of MAGL with IC50 of 8 nM and 4 µM for inhibition of MAGL and FAAH in mouse brain membranes respectively. Target: Lipase. Smiles: OC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc2OCOc2c1)c1ccc2OCOc2c1. References: Long JZ, et al. Nat Chem Biol, 2009, 5(1), 37-44.
| Schlagworte: | JZL184 |
| Anwendung: | Selective, potent monoglyceride lipase (MGL) inhibitor |
| CAS | 1101854-58-3 |
| MW: | 520.49 D |
ab 34,00 €
