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Ubiquitin Isopeptidase Inhibitor I, G5
Artikelnummer: TGM-T17192-100mg
Description: Ubiquitin Isopeptidase Inhibitor I, G5 is a caspase-independent inducer of cell necrosis that induces cell death via the death receptor pathway (IC50 of 1.76 and 1.6 µM in E1A and E1A/C9DN cells, respectively). Target: Apoptosis. Smiles:...
| Schlagworte: | NSC144303 |
| Anwendung: | Ubiquitin Isopeptidase inhibitor |
| CAS | 108477-18-5 |
| MW: | 414.39 D |
ab 73,00 €
Ubiquitin Isopeptidase Inhibitor I
Artikelnummer: Cay21006-10
Ubiquitin isopeptidase inhibitor I induces caspase activation and apoptosis (IC50 = ~1.7 µM) through a Bcl-2-dependent and apoptosome-independent mitochondrial pathway that selectively inhibits ubiquitin isopeptidase activity (IC50 = ~30 µM). It has also been shown to induce necrosis in apoptosis-resistant DKO...
| Schlagworte: | NSC 144303, tetrahydro-3,5-bis[(4-nitrophenyl)methylene]-4H-thiopyran-4-one, 1,1-dioxide |
| Anwendung: | Ubiquitin isopeptidase inhibitor |
| CAS | 108477-18-5 |
| MW: | 414.4 D |
ab 130,00 €
