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LY-2584702 tosylate salt
Artikelnummer: TGM-T1746-100mg
Description: LY-2584702 tosylate salt, a selective ATP-competitive p70S6K inhibitor, is being used in clinical trials for cancer treatment. Target: S6 Kinase. Smiles: Cc1ccc(cc1)S(O)(=O)=O.Cn1cc(nc1C1CCN(CC1)c1ncnc2[nH]ncc12)-c1ccc(F)c(c1)C(F)(F)F. References: Tolcher A, et al. Eur J Cancer. 2014, 50(5), 867-875.
| Schlagworte: | LY2584702 tosylate |
| Anwendung: | p70S6K signaling inhibitor |
| CAS | 1082949-68-5 |
| MW: | 617.62 D |
ab 31,00 €
LY2584702 (tosylate)
Artikelnummer: Cay15320-1
LY2584702 is an inhibitor of p70 ribosomal S6 kinase (p70S6K, IC50 = 0.004 µM). It is selective for p70S6K over a panel of 83 kinases. LY2584702 inhibits the phosphorylation of S6 in HCT116 colon cancer cells (IC50 = 0.1-0.24 µM) and decreases triglyceride levels and apolipoprotein B secretion in tuberous sclerosis...
| Schlagworte: | LYS6K2,... |
| Anwendung: | p70S6K signaling inhibitor |
| CAS | 1082949-68-5 |
| MW: | 617.6 D |
ab 44,00 €
