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CY-09
Artikelnummer: TGM-T4164-100mg
Description: CY-09 is an NLRP3 inhibitor. Target: NOD, NOD-like Receptor (NLR). Smiles: OC(=O)c1ccc(C=C2SC(=S)N(Cc3cccc(c3)C(F)(F)F)C2=O)cc1. References: Jiang H, et al. Identification of a selective and direct NLRP3 inhibitor to treat inflammatory disorders. J Exp Med. 2017 Nov 6,214(11):3219-3238.
| Schlagworte: | CY 09 |
| Anwendung: | NLRP3 inhibitor |
| CAS | 1073612-91-5 |
| MW: | 423.43 D |
ab 47,00 €
CY-09
Artikelnummer: Cay33353-10
CY-09 is a NOD-like receptor protein 3 (NLRP3) inhibitor. It selectively inhibits NLRP3 ATPase activity over the ATPase activity of NLRP1, NLRC4, NOD2, and RIG-I at 1 µM. CY-09 binds directly to the ATP-binding motif of the NLRP3 NACHT domain (Kd = 500 nM) and suppresses NLRP3 inflammasome assembly. It inhibits...
| Schlagworte: | 4-[[4-oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]-benzoic acid |
| Anwendung: | NLRP3 inhibitor |
| CAS | 1073612-91-5 |
| MW: | 423.4 D |
ab 125,00 €
