Zu "1072833-77-2" wurden 4 Artikel gefunden!
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Ixazomib
Artikelnummer: TGM-T2122-100mg
Description: Ixazomib (MLN2238) , a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (beta5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also inhibits the caspase-like (beta1) and trypsin-like (beta2) proteolytic sites...
| Schlagworte: | MLN2238 |
| CAS | 1072833-77-2 |
| MW: | 361.03 D |
ab 41,00 €
![Ixazomib [MLN2238]](https://www.biomol.com/media/image/53/8f/f3/AG-CR1-3670-M001_200x200.png "Ixazomib [MLN2238]")
Ixazomib [MLN2238]
Artikelnummer: AG-CR1-3670-M001
Synthetic. Chemical. CAS: 1072833-77-2. Formula: C14H19BCl2N2O4. MW: 361. Synthetic. Potent selective and reversible proteasome inhibitor (all proteolytic subunits). Targets the chymotrypsin-like beta5 subunit of the constitutive 20S proteasome (IC50=3.4nM). Cross-reacts and inhibits the trypsin-like beta2 subunit...
| Schlagworte: | (R)-1-(2-(2,5-Dichlorobenzamido)acetamido)-3-methylbutylboronic acid |
| Anwendung: | Proteasome inhibitor |
| CAS | 1072833-77-2 |
| MW: | 361 D |
ab 44,00 €
MLN-2238
Artikelnummer: LKT-M4455.1
MLN-2238 is a proteasome inhibitor that modulates miR33b, a tumor suppressor microRNA. MLN-2238 exhibits anticancer activity, downregulating Pim-1 activity in multiple myeloma cells.
| Schlagworte: | Ixazomib |
| Anwendung: | Proteasome subunit beta type-5 inhibitor |
| CAS | 1072833-77-2 |
| MW: | 361.03 D |
ab 77,00 €
MLN2238
Artikelnummer: Cay18385-10
MLN2238 is an inhibitor of the beta5 subunit of the 20S proteasome (IC50 = 3.4 nM in a cell-free assay) and an active metabolite of MLN9708 (Cay-18386). It is formed from MLN9708 via hydrolysis in plasma. MLN2238 is selective for the chymotrypsin-like beta5 subunit over the caspase-like beta1 and trypsin-like beta2...
| Schlagworte: | B-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-boronic acid |
| Anwendung: | Proteasome PSMB5 inhibitor |
| CAS | 1072833-77-2 |
| MW: | 361 D |
ab 46,00 €
