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NEU
SNT-207707 (hydrochloride)
Artikelnummer: Cay41524-1
SNT-207707 is a melanocortin receptor 4 (MC4R) antagonist (IC50 = 5 nM). It increases food intake in mice when administered at a dose of 20 mg/kg. SNT-207707 (30 mg/kg per day) inhibits tumor-induced weight loss without inhibiting tumor growth in a C26 murine colon carcinoma model of tumor-induced cachexia.Formal...
| Schlagworte: | 2-(4-cyanophenyl)-N,N-bis(3-methylbutyl)-3-[3-(1-pyrrolidinyl)propyl]-imidazo[1,2-a]pyridine-6-carboxamide, monohydrochloride |
| Anwendung: | MC4R antagonist |
| CAS | 1064662-40-3 |
| MW: | 550.2 D |
ab 90,00 €
SNT-207707
Artikelnummer: TGM-T12944-100mg
Description: SNT-207707 is a potent, selective and orally active antagonist of melanocortin MC-4 receptor(IC50 of 8 nM (binding) and 5 nM (function) on the MC-4 receptor). Target: Others. Smiles: Cl.CC(C)CCN(CCC(C)C)C(=O)c1ccc2nc(c(CCCN3CCCC3)n2c1)-c1ccc(cc1)C#N. References: Weyermann P, et al. Orally available...
| CAS | 1064662-40-3 |
| MW: | 550.18 D |
ab 1.491,00 €
