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PND-1186
PND-1186

Artikelnummer: TGM-T1950-100mg

Description: PND-1186 (VS-4718) is a specific and reversible FAK inhibitor with an IC50 of 1.5 nM. Target: Apoptosis, FAK. Smiles: CNC(=O)c1ccccc1Nc1cc(Nc2ccc(cc2OC)N2CCOCC2)ncc1C(F)(F)F. References: Tanjoni I, et al. Cancer Biol Ther. 2010, 9(10), 764-777.
Schlagworte: VS-4718, SR-2516, PND 1186, PND1186
Anwendung: FAK inhibitor
CAS 1061353-68-1
MW: 501.5 D
ab 48,00 €
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PND1186
PND1186

Artikelnummer: Cay17668-5

PND1186 is a potent reversible focal adhesion kinase (FAK) inhibitor with an IC50 value of 1.5 nM against the recombinant enzyme and 100 nM in breast carcinoma cells. It promotes 4T1 breast carcinoma and ID8 ovarian carcinoma cell apoptosis when grown in anchorage-independent 3D cultures but had limited efficacy in...
Schlagworte: SR 2516, VS-4718, 2-[[2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-5-(trifluoromethyl)-4-pyridinyl]amino]-N-methyl-benzamide
Anwendung: FAK inhibitor
CAS 1061353-68-1
MW: 501.5 D
ab 77,00 €
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VS-4718
VS-4718

Artikelnummer: LKT-V720004.5

Focal adhesion kinase (FAK) inhibitor.
Schlagworte: VS-4718, VS 4718, VS4718, SR-2516, SR 2516, SR2516, PND-1186, PND 1186, PND1186
Anwendung: FAK inhibitor
CAS 1061353-68-1
MW: 501.51 D
ab 117,00 €
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