Zu "104987-11-3" wurden 5 Artikel gefunden!
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Tacrolimus
Artikelnummer: TGM-T2144-10mg
Description: Tacrolimus (Fujimycin) can bind FKBP12 to form a high-affinity complex (Ki: 0.2 nM) which inhibits the activity of the calcium/calmodulin-dependent protein phosphatase. Target: mTOR, Autophagy, Phosphatase, Antibiotic, Antibacterial, Others. Smiles:...
| Schlagworte: | Fujimycin, FK506, FR900506 |
| CAS | 104987-11-3 |
| MW: | 804.02 D |
ab 40,00 €
FK-506
Artikelnummer: Cay10007965-5
FK-506 is a potent immunosuppressant in the same molecular class as cyclosporin A (Cay-12088) and rapamycin (Cay-13346). Its mechanism of action involves the formation of a high affinity complex (Ki = 0.2 nM) with FK-506 binding protein 12 (FKBP12). This complex then inhibits the activity of the...
| Schlagworte: | Tacrolimus,... |
| Anwendung: | Immunosuppressant |
| CAS | 104987-11-3 |
| MW: | 804 D |
ab 49,00 €
Tacrolimus
Artikelnummer: LKT-T0008.5
An immunosuppressant commonly used in transplant operations to prevent graft-versus-host disease.
| Schlagworte: | FK506, FK-506, fujimycin |
| Anwendung: | Immunomodulator |
| CAS | 104987-11-3 |
| MW: | 804,02 D |
ab 63,00 €
FK-506
Artikelnummer: AG-CN2-0047-M025
Potent immunosuppressant (as cyclosporin A and rapamycin). Suppresses proliferation of cytotoxic T cells and inhibits the production of T cell-derived mediators such as interleukin-2 (IL-2). Forms a complex with FK-506 binding protein 12 (FKBP12). Inhibits the activity of the calcium/calmodulin-dependent protein...
| Schlagworte: | Tacrolimus, Fujimycin |
| Anwendung: | Immunosuppressant |
| Wirt: | Streptomyces FCZ0311 |
| CAS | 104987-11-3 |
ab 17,00 €
FK-506 (Fujimycin, Tacrolimus)
Artikelnummer: F4522-01.10
FK-506 is a potent immunosuppressant and in vitro T cell proliferation blocker. It has been shown to disrupt calcineurin (also known as CaN or phosphatase 2B)-mediated signal transduction in T lymphocytes. The compound interacts with its FK506-binding protein-12 (FKBP12). The resulting complex, in turn,...
| CAS | 104987-11-3 |
| MW: | 804.02 |
ab 327,00 €
