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MI-2 [MALT1 Inhibitor]
MI-2 [MALT1 Inhibitor]

Artikelnummer: AG-CR1-3661-M005

White to off-white solid. Soluble in DMSO (30mg/ml) or ethanol (5mg/ml). Highly potent and selective irreversible MALT1 inhibitor (IC50=5.8&mu,M). Binds directly to MALT1 and suppresses protease function, Decreases NF-kappaB activity induced by MALT1. Inhibits cell proliferation and MALT1-mediated cleavage activity....
Schlagworte: 2-Chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl]phenylacetamide, ALB-H03200218
Anwendung: Highly potent and selective irreversible MALT1 inhibitor
CAS 1047953-91-2
MW: 455,7 D
ab 99,00 €
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MI 2
MI 2

Artikelnummer: Cay23437-1

MI 2 is an inhibitor of the paracaspase MALT1 with an IC50 value of 5.84 µM in a fluorescence assay. It inhibits the growth of MALT1-dependent activated B cell-like diffuse large B cell lymphoma (ABC-DLBCL) cell lines (GI50s = 0.2, 0.5, 0.4, and 0.4 µM for HBL-1, TMD8, OCI-Ly3, and OCI-Ly10 cells, respectively). MI...
Schlagworte: 2-chloro-N-[4-[5-(3,4-dichlorophenyl)-3-(2-methoxyethoxy)-1H-1,2,4-triazol-1-yl]phenyl]-acetamide
Anwendung: MALT1 inhibitor
CAS 1047953-91-2
MW: 455.7 D
ab 44,00 €
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MALT1 inhibitor MI-2
MALT1 inhibitor MI-2

Artikelnummer: TGM-T2350-100mg

Description: MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor. Target: MALT. Smiles: COCCOc1nc(-c2ccc(Cl)c(Cl)c2)n(n1)-c1ccc(NC(=O)CCl)cc1. References: Fontan L, et al. Cancer Cell. 2012, 22(6), 812-824.
Schlagworte: MI 2, MALT1 inhibitor, MI 2 (MALT1 inhibitor)
Anwendung: MALT1 inhibitor
CAS 1047953-91-2
MW: 455.72 D
ab 31,00 €
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