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Dacomitinib hydrate
Artikelnummer: TGM-T19965-100mg
Description: Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of tyrosine kinases. Dacomitinib specifically and irreversibly binds to and inhibits human EGFR subtypes, resulting in inhibition of proliferation and...
| Schlagworte: | PF-00299804, PF299804, PF 00299804, PF-299804, PF00299804, PF 299804 |
| CAS | 1042385-75-0 |
| MW: | 487.96 D |
ab 32,00 €
Dacomitinib (hydrate)
Artikelnummer: LKT-D0006.1
A potent, irreversible pan-ErbB inhibitor, mostly to EGFR with IC50 of 6 nM, effective against NSCLCs with EGFR or ERBB2 mutations (resistant to gefitinib) as well as those harboring the EGFR T790M mutation.
| Schlagworte: | PF-00299804 |
| Anwendung: | erbB / EGFR inhibitor |
| CAS | 1042385-75-0 |
| MW: | 488 D |
ab 149,00 €
