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ML162
ML162

Artikelnummer: TGM-T8970-100mg

Description: ML162 is an inhibitor of GPX4 that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC50s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively). Target: GPX, Glutathione Peroxidase, Ferroptosis. Smiles:...
Anwendung: GPX4 inhibitor, antitumor agent
CAS 1035072-16-2
MW: 477.4 D
ab 89,00 €
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ML-162
ML-162

Artikelnummer: Cay20455-1

ML-162 is an inhibitor of glutathione peroxidase 4 (GPX4). It decreases GPX4 levels in MDA-MB-231 breast cancer cells, as well as the viability of BT-549 breast cancer cells, an effect that is enhanced by alpha-eleostearic acid (9(Z),11(E),13(E)-octadecatrienoic acid, Cay-10008349). ML-162 is also selectively lethal...
Schlagworte: alpha-[(2-chloroacetyl)(3-chloro-4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thiopheneacetamide
Anwendung: GPX4 inhibitor, antitumor agent
CAS 1035072-16-2
MW: 477.4 D
ab 38,00 €
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