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CRT5
Artikelnummer: TGM-T21795-10mg
Description: CRT5, a pyrazine benzamide, is a potent and selective PKD inhibitor. It inhibits VEGF-induced phosphorylation of three PKD substrates (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively), histone deacetylase 5, CREB (cAMP-response-element-binding protein), and HSP27 (heat-shock protein 27)...
| CAS | 1034297-58-9 |
| MW: | 454.56 D |
ab 77,00 €
CRT5
Artikelnummer: Cay18532-5
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein transport. CRT5 is a pyrazine benzamide that prevents...
| Schlagworte: | CRT0066051, 3-[6-amino-5-(6-ethoxy-2-naphthalenyl)-3-pyridinyl]-N-[2-(dimethylamino)ethyl]-benzamide |
| Anwendung: | PKD activation inhibitor |
| CAS | 1034297-58-9 |
| MW: | 454.6 D |
ab 44,00 €
