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AEM1
Artikelnummer: TGM-T8979-100mg
Description: AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer. AEM1 acts by broadly decreasing the expression of NRF2 controlled genes, sensitizing A549 cells to various chemotherapeutic agents, and inhibiting the growth of A549 cells in vitro and in vivo. Target: Nrf2. Smiles:...
| Anwendung: | Nrf2-induced gene transcription inhibitor |
| CAS | 1030123-90-0 |
| MW: | 379.41 D |
ab 49,00 €
AEM1
Artikelnummer: Cay18321-1
Cancer cell survival appears partly dependent on antioxidative enzymes, whose expression is regulated by the Keap1-Nrf2 pathway, to quench potentially toxic reactive oxygen species generated by their metastatic transformation. AEM1 is an inhibitor of gene expression induced by nuclear erythroid 2-related factor 2...
| Schlagworte: | N-(1,3-benzodioxol-5-ylmethyl)-5-(4-fluorophenyl)-thieno[2,3-d]pyrimidin-4-amine |
| Anwendung: | Nrf2-induced gene transcription inhibitor |
| CAS | 1030123-90-0 |
| MW: | 379.4 D |
ab 44,00 €
