Zu "1028486-01-2" wurden 3 Artikel gefunden!
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MLN8237
Artikelnummer: Cay13602-1
MLN8237 is an inhibitor of Aurora A kinase (IC50 = 1 nM). It is selective for Aurora A over Aurora B kinase (IC50 = 396.5 nM). MLN8237 (50 nM) induces cell cycle arrest at the G2/M phase and chromosomal misalignment in HCT116 colon cancer cells. It inhibits tumor growth in a Calu-6 non-small cell lung cancer (NSCLC)...
| Schlagworte: | Alisertib, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy benzoic acid |
| Anwendung: | Aurora A kinase inhibitor |
| CAS | 1028486-01-2 |
| MW: | 518.9 D |
ab 43,00 €
MLN8237
Artikelnummer: LKT-M4652.10
MLN8237 inhibits aurora kinase A (AurA) preventing mitotic spindle formation and proper completion of mitosis. MLN8237 exhibits anticancer chemotherapeutic activity and is currently in clinical trials as a potential treatment for multiple myeloma, non-Hodgkin's lymphoma, and chronic lymphocytic leukemia (CLL). In...
| Schlagworte: | Alisertib |
| Anwendung: | Aurora A kinase inhibitor |
| CAS | 1028486-01-2 |
| MW: | 518.92 D |
ab 156,00 €
MLN 8237
Artikelnummer: 281903.10
MLN8237 (Alisertib) is an orally available selective aurora A kinase inhibitor.
| Schlagworte: | 4-[[9-Chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy-benzoic acid, Alisertib,... |
| Anwendung: | Antineoplastic, Serine/threonine kinase inhibitor, Aurora kinase inhibitor |
| CAS | 1028486-01-2 |
| MW: | 518.92 D |
439,00 €
