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CL097
Artikelnummer: TGM-T38423-100mg
Description: CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-stimulated ROS production. Target: Reactive Oxygen Species, TLR. Smiles: CCOCc1nc2c([nH]1)c(N)nc1ccccc21. References: Karama Makni-Maalej, et...
| Schlagworte: | CL097 |
| Anwendung: | TLR7 / TLR8 dual agonist |
| CAS | 1026249-18-2 |
| MW: | 242.28 D |
ab 57,00 €
CL097
Artikelnummer: Cay39513-1
CL097 is a dual agonist of toll-like receptor 7 (TLR7) and TLR8. It induces activation of NF-kappaB in HEK293 cells expressing human TLR7 or TLR8 when used at concentrations of 0.1 and 1 µg/ml, respectively. CL097 induces TNF-alpha production and enhances LPS- or hyaluronic acid-induced TNF-alpha, IL-10, and IL-12...
| Schlagworte: | 2-(ethoxymethyl)-3H-imidazo[4,5-c]quinolin-4-amine |
| Anwendung: | TLR7 / TLR8 dual agonist |
| CAS | 1026249-18-2 |
| MW: | 242.3 D |
ab 40,00 €
