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ZM39923 hydrochloride
Artikelnummer: TGM-T6145-100mg
Description: ZM39923 hydrochloride (JAK3 Inhibitor IV) is an JAK1/3 inhibitor with pIC50 of 4.4/7.1, almost no activity to JAK2 and modestly potent to EGFR, also found to be sensitive to transglutaminase. Target: EGFR, Others, JAK. Smiles: Cl.CC(C)N(CCC(=O)C1=CC=C2C=CC=CC2=C1)CC1=CC=CC=C1. References: Brown GR, et...
| Schlagworte: | JAK3 Inhibitor IV, ZM 39923 HCl |
| Anwendung: | JAK3 inhibitor |
| CAS | 1021868-92-7 |
| MW: | 367.91 D |
ab 55,00 €
ZM 39923 (hydrochloride)
Artikelnummer: Cay16729-1
ZM 39923 is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 µM, respectively). In the absence of the reducing agent dithiothreitol, ZM 39923 also inhibits human tissue transglutaminase 2 (TGM2) and the...
| Schlagworte: | JAK3 Inhibitor IV, Janus-Associated Kinase 3 Inhibitor IV,... |
| Anwendung: | JAK3 inhibitor |
| CAS | 1021868-92-7 |
| MW: | 367.9 D |
ab 61,00 €
