Zu "102052-95-9" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
3-Deazaneplanocin A
Artikelnummer: Cay13828-1
3-Deazaneplanocin A is a cyclopentenyl analog of 3-deazaadenosine, originally synthesized as an inhibitor of S-adenosyl-L-homocysteine hydrolase. It has been shown to deplete EZH2 levels and to inhibit trimethylation of lysine 27 on histone H3 in cultured human acute myeloid leukemia (AML) HL-60 and OCI-AML3 cells...
| Schlagworte: | DZNep, NSC 617989, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol |
| Anwendung: | S-adenosyl-L-homosysteine hydrolase inhibitor |
| CAS | 102052-95-9 |
| MW: | 262.3 D |
ab 133,00 €
3-Deazaneplanocin A
Artikelnummer: TGM-T6292-1mg
Description: 3-Deazaneplanocin A (DZNep) is a promising epigenetic anticancer agent that inhibits the cellular enhancer of zeste homolog 2 (EZH2) protein. Target: Histone Methyltransferase. Smiles: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CC3)C=C(CO)[C@H]1O. References: Avan A, et al. Mol Cancer Ther. 2012 Aug,11(8):1735-46.
| CAS | 102052-95-9 |
| MW: | 262.26 D |
ab 159,00 €
