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CAY10581
Artikelnummer: TGM-T73351-10mg
Description: CAY10581, a derivative of pyranonaphthoquinone, serves as a highly specific and reversible uncompetitive inhibitor of IDO, demonstrating potency with an IC50 value of 55 nM. Target: Others. Smiles: N(CC1=CC=CC=C1)[C@H]2C3=C(C(=O)C=4C(C3=O)=CC=CC4)OC(C)(C)[C@H]2O
| Anwendung: | Indoleamine 2,3-dioxygenase inhibitor |
| CAS | 1018340-07-2 |
| MW: | 363.41 D |
ab 91,00 €
CAY10581
Artikelnummer: Cay16838-1
The enzyme indoleamine 2,3-dioxygenase (IDO) has been implicated in mediating pathological immunosuppression associated with certain diseases, including cancer. Several naphthoquinones inhibit IDO in vitro and in cells, but at low (µM) potency. Importantly, naphthoquinones reduce tumor growth in wild type mice but...
| Schlagworte: | (±)3,4-dihydro-3-hydroxy-2,2-dimethyl-4-[(phenylmethyl)amino]-2H-naphtho[2,3-b]pyran-5,10-dione |
| Anwendung: | Indoleamine 2,3-dioxygenase inhibitor |
| CAS | 1018340-07-2 |
| MW: | 363.4 D |
ab 50,00 €
