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6(5H)-Phenanthridinone
Artikelnummer: TGM-T72017-10mg
Description: 6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2. It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells. 6(5H)-Phenanthridinone reduces NF-kappaB-induced transcription of the genes encoding TNF-alpha, IL-2, and IFN-gamma in...
| Anwendung: | PARP1/2 inhibitor |
| CAS | 1015-89-0 |
| MW: | 195.22 D |
ab 86,00 €
6(5H)-Phenanthridinone
Artikelnummer: Cay28730-10
6(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose) polymerase 1 (PARP1) and PARP2 (EC50s = 10.2 and 36.3 µM, respectively, in yeast cells expressing the human enzymes). It decreases radiation-induced PARP activity and proliferation of RDM4 murine lymphoma cells when used at a concentration of 50 µM....
| Schlagworte: | NSC 11021, NSC 40943, NSC 61083 |
| Anwendung: | PARP1/2 inhibitor |
| CAS | 1015-89-0 |
| MW: | 195.2 D |
ab 48,00 €
