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PF-04691502
PF-04691502

Artikelnummer: Cay15017-5

PF-04691502 is an inhibitor of PI3Kalpha, -beta, -delta, and -gamma and mammalian target of rapamycin (mTOR, Kis = 1.8, 2.1, 1.6, 1.9, and 16 nM, respectively, for the human enzymes). It decreases the proliferation of BT-20 breast cancer, SKOV3 ovarian cancer, and U87MG glioblastoma cells (IC50s = 313, 188, and 179...
Schlagworte: HNC-VP-L, PF-502,...
Anwendung: PI3K/mTOR inhibitor
CAS 1013101-36-4
MW: 425.5 D
ab 119,00 €
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PF-04691502
PF-04691502

Artikelnummer: LKT-P2002.1

PF-04691502 inhibits PI3K and mTORC1/2, exhibiting anticancer chemotherapeutic and anti-angiogenic activities. In nasopharyngeal carcinoma cells, PF-04691502 induces G0/G1 cell cycle arrest and apoptosis, inhibiting proliferation. In similar animal models, PF-04691502 decreases tumor volume and weight. Additionally,...
Anwendung: PI3K and mTOR inhibitor
CAS 1013101-36-4
MW: 461.51 D
ab 180,00 €
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