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Tenovin-6 Hydrochloride
Tenovin-6 Hydrochloride

Artikelnummer: TGM-T8480-100mg

Description: Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 µM, 10 µM, and 67 µM for SirT1, SirT2, and SirT3, respectively), and is also a potent p53 activator . Target: Autophagy, Sirtuin, p53, Dehydrogenase, HDAC. Smiles: Cl.CN(C)CCCCC(=O)Nc1ccc(NC(=S)NC(=O)c2ccc(cc2)C(C)(C)C)cc1....
Anwendung: SIRT inhibitor
CAS 1011301-29-3
MW: 491.09 D
ab 34,00 €
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Tenovin-6 (hydrochloride)
Tenovin-6 (hydrochloride)

Artikelnummer: Cay13086-1

The tumor suppressor function of p53 hinges on its ability to function as a transcription factor. Tenovin-6 is an analog of tenovin-1, a small molecule activator of p53 transcriptional activity. At 10 µM, this compound is slightly more effective than tenovin-1 at elevating p53 activity in MCF-7 cells and reduces...
Schlagworte: N-[[[4-[[5-(dimethylamino)-1-oxopentyl]amino]phenyl]amino]thioxomethyl]-4-(1,1-dimethylethyl)-benzamide
Anwendung: SIRT inhibitor
CAS 1011301-29-3
MW: 491.1 D
ab 66,00 €
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