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TFAP
Artikelnummer: TGM-T4643-100mg
Description: TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor. Target: Endogenous Metabolite, COX. Smiles: Nc1ccc(NC(=O)c2ccc(cc2)C(F)(F)F)nc1. References: Kakuta H, et al. Identification of urine metabolites of TFAP, a cyclooxygenase-1 inhibitor. Bioorg...
| Schlagworte: | N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide |
| Anwendung: | COX-1 inhibitor |
| CAS | 1011244-68-0 |
| MW: | 281.23 D |
ab 32,00 €
TFAP
Artikelnummer: Cay26745-1
TFAP is an inhibitor of COX-1 (IC50 = 0.8 µM). It is selective for COX-1 over COX-2 (IC50 = 210 µM). TFAP (10 and 30 mg/kg) reduces acetic acid-induced writhing in mice and has analgesic activity in the formalin test in rats when administered at a dose of 30 mg/kg. It does not induce gastric damage in rats when...
| Schlagworte: | N-(5-amino-2-pyridinyl)-4-(trifluoromethyl)-benzamide |
| Anwendung: | COX-1 inhibitor |
| CAS | 1011244-68-0 |
| MW: | 281.2 D |
ab 43,00 €
