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CH5132799
Artikelnummer: TGM-T2619-100mg
Description: CH5132799 has been used in trials studying the treatment of Solid Tumors. Target: mTOR, PI3K. Smiles: CS(=O)(=O)N1CCc2c1nc(nc2-c1cnc(N)nc1)N1CCOCC1. References: Tanaka H, et al, Clin Cancer Res, 2011, 17(10), 3272-3281.
| Anwendung: | PI3K alpha / beta / delta / gamma inhibitor |
| CAS | 1007207-67-1 |
| MW: | 377.42 D |
ab 57,00 €
CH5132799
Artikelnummer: LKT-C2802.1
CH5132799 is an inhibitor of PI3K that is somewhat selective for p110 isoforms. This compound exhibits anticancer chemotherapeutic activity, inhibiting cell proliferation and tumor growth in breast cancer, ovarian cancer, prostate cancer, and endometrial cancer models.
| Anwendung: | PI3K inhibitor |
| CAS | 1007207-67-1 |
| MW: | 377.42 D |
ab 136,00 €
CH-5132799
Artikelnummer: SYN-1146-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. CH5132799 selectively inhibits class I PI3Kalpha with an IC(50) value of 14nM. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
| Schlagworte: | CH-5132799 |
| Anwendung: | PI3K alpha inhibitor |
| CAS | 1007207-67-1 |
| MW: | 377,4 D |
ab 165,00 €
CH5132799
Artikelnummer: Cay26410-10
CH5132799 is an inhibitor of class I PI3K isoforms (IC50s = 14, 120, 500, and 36 nM for PI3Kalpha, PI3Kbeta, PI3Kdelta, and PI3Kgamma, respectively). It is selective for these PI3K isoforms over PI3KC2alpha and PI3KC2beta, which are class II PI3Ks, Vps34, a class III PI3K, and mTOR (IC50s = 5,300, >10,000, >10,000,...
| Schlagworte: | 5-[6,7-dihydro-7-(methylsulfonyl)-2-(4-morpholinyl)-5H-pyrrolo[2,3-d]pyrimidin-4-yl]-2-pyrimidinamine |
| Anwendung: | PI3K alpha / beta / delta / gamma inhibitor |
| CAS | 1007207-67-1 |
| MW: | 377.4 D |
ab 266,00 €
