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CVT-10216
Artikelnummer: TGM-T15022-100mg
Description: CVT-10216 is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50: 29 nM). CVT-10216 also has inhibitory effect of ALDH-1 (IC50: 1.3 µM). CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects. Target: Dehydrogenase....
| Anwendung: | ALDH2 inhibitor |
| CAS | 1005334-57-5 |
| MW: | 465.48 D |
ab 43,00 €
CVT-10216
Artikelnummer: Cay18318-1
Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme involved in the major oxidative pathway of alcohol metabolism. CVT-10216 is a reversible inhibitor of ALDH2 (IC50 = 29 nM) that demonstrates >40-fold selectivity for ALDH2 over the cytosolic isoform, ALDH1. CVT-10216 has been reported to reduce excessive...
| Schlagworte: | GS-455534, 3-[[[3-[4-[(methylsulfonyl)amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]-benzoic acid |
| Anwendung: | ALDH2 inhibitor |
| CAS | 1005334-57-5 |
| MW: | 465.5 D |
ab 54,00 €
