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Cobicistat
Artikelnummer: TGM-T6246-100mg
Description: Cobicistat (GS-9350) is a carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, with which it is used in combination, for the treatment of HIV INFECTIONS. Target: P450, HIV Protease. Smiles:...
| Schlagworte: | Tybost, GS-9350 |
| Anwendung: | Antiviral (potentiator), CYP3A inhibitor |
| CAS | 1004316-88-4 |
| MW: | 776.02 D |
ab 40,00 €
Cobicistat
Artikelnummer: Cay23433-10
Cobicistat is an inhibitor of the cytochrome P450 (CYP) isomer CYP3A (IC50s = 30-285 nM for CYP3A metabolism of various HIV protease inhibitors). It is selective for CYP3A over other CYP isomers (IC50 = >25 µM for CYP1A2, 2C8, 2C9, and 2C19). Cobicistat does not inhibit HIV-1 protease (IC50 = >30 µM) or affect HIV...
| Schlagworte: | GS-9350,... |
| Anwendung: | CYP3A inhibitor |
| CAS | 1004316-88-4 |
| MW: | 776 D |
ab 52,00 €
