Zu "931," wurden 16 Artikel gefunden!

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HGF R/c-MET, Recombinant, Mouse, aa25-931, hIgG-His-Tag
HGF R/c-MET, Recombinant, Mouse, aa25-931, hIgG-His-Tag

Artikelnummer: 532316.100

HGFR, also known as c-Met, is a receptor tyrosine kinase (RTK) that has been shown to be overexpressed and/or mutated in a variety of malignancies. It regulates many physiological processes including proliferation, scattering, morphogenesis and survival. This ligand binding at the cell surface induces...
Schlagworte: Met, SF receptor, EC=2.7.10.1, HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor,...
Exprimiert in: Insect cells
Ursprungsart: mouse
MW: 127.8 kD
ab 470,00 €
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Insulin-Like Growth Factor 1, Receptor, Recombinant, Human, aa763-931, His-Tag (IGF1R)
Insulin-Like Growth Factor 1, Receptor, Recombinant,...

Artikelnummer: 517963.100

Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell. Ligand...
Schlagworte: IGF1R, EC=2.7.10.1
Exprimiert in: E.coli
Ursprungsart: human
MW: 23.4 kD
ab 511,00 €
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Anti-JAK2 (Ab-931)
Anti-JAK2 (Ab-931)

Artikelnummer: ABD-8B8118.50

Custom conjugation services for this antibody as available (eg. labeling of Anti-JAK2 (Ab-931) with HRP. Available labels are AF: AF350, AF488, AF555, AF594, AF647, AF680, AF700, AF750. Proteins: HRP, Alkaline Phosphatase, Streptavidin. Tandems: APC, APC/Cy7, APC/AF750, APC/iFluor(TM) 700, APC/iFluor(TM) 750, PE,...
Schlagworte: Anti-JAK-2, Anti-Janus kinase 2, Anti-Tyrosine-protein kinase JAK2, JAK2 (Ab-931) Antibody
Anwendung: IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
601,00 €
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Simurosertib
Simurosertib

Artikelnummer: Cay32519-5

Simurosertib is an inhibitor of cell division cycle 7 (Cdc7) kinase (IC50 = 0.26 nM). It is selective for Cdc7 over cyclin-dependent kinase 2 (Cdk2) and Rho-associated kinase 1 (ROCK1, IC50s = 6,300 and 430 nM, respectively). It inhibits phosphorylation of DNA replication licensing factor MCM2 in HeLa cells (IC50 =...
Schlagworte: TAK-931, 2-(2S)-1-azabicyclo[2.2.2]oct-2-yl-6-(3-methyl-1H-pyrazol-4-yl)-thieno[3,2-d]pyrimidin-4(3H)-one
Anwendung: Cdc7 kinase inhibitor
CAS 1330782-76-7
MW: 341.4 D
ab 60,00 €
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